Stress-specific expression of HSPA and DNAJ chaperones regulated by NRF2/HSF1 in neurodegenerative conditions

  • Mol Cell Biochem. 2026 Jan 29. doi: 10.1007/s11010-026-05484-3.
Siraj Fatima  1  2 ,  Anurag Gupta  1 ,  Smriti Priya  3  4
Affiliations
  • 1. Systems Toxicology Group, Food, Drug & Chemical, Environment and Systems Toxicology (FEST) Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.
  • 2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
  • 3. Systems Toxicology Group, Food, Drug & Chemical, Environment and Systems Toxicology (FEST) Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India. [email protected].
  • 4. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. [email protected].
PMID: 41609899 DOI: 10.1007/s11010-026-05484-3
Keywords
DNAJB; HSF1; HSPA; Molecular chaperones; NRF2; Neurodegenerative disease; Proteotoxicity.
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