Sf3b1 - splicing factor 3b, subunit 1 Gene

Also Known as Sap155

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84486

Summary

Predicted to enable chromatin binding activity; mRNA binding activity; and splicing factor binding activity. Predicted to be involved in spliceosomal complex assembly. Predicted to act upstream of or within anterior/posterior pattern specification; blastocyst formation; and mRNA splicing, via spliceosome. Located in nucleus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and myelodysplastic syndrome. Orthologous to human SF3B1 (splicing factor 3b subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Sf3b1 Products (1)

mRNA Protein Name
NM_053426.1 NP_445878.1 splicing factor 3B subunit 1
Protein Preferred Names Protein Names

splicing factor 3B subunit 1

  • splicing factor 3b, subunit 1, 155kD

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-111517 H3B-8800 Inhibitor 98.85% Phase 1

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16399 Pladienolide B Inhibitor 99.20% Unkown
HY-16466 Spliceostatin A 96.64% Unkown
HY-141881 PROTAC-O4I2 Degrader 99.56% Unkown
HY-168534 WX-02-23 Modulator 99.88% Unkown
HY-18772 O4I2 Ligand 99.18% Unkown
HY-181421 WX-02-43 Ligand 99.49% Unkown
HY-15867 Meayamycin B Inhibitor / Unkown
HY-122637 Sudemycin K Inhibitor / Unkown
HY-133924 18-Deoxyherboxidiene Inhibitor / Unkown
HY-120907 Sudemycin E Ligand / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sf3b1 NCBI NCBI:23451