FGFR-IN-22
FGFR-IN-22 (Compound 23) is a FGFR inhibitor with IC50s of 0.631, 1.26, 0.851 and 1 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-22 effectively inhibits cell proliferation that depends on the FGFR1 and FGFR3 signaling pathway. FGFR-IN-22 can be used for cancers such as chronic lymphocytic leukemia (CLL) research.
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- CAS No.: 1431872-18-2
- Formule: C23H21FN8O2
- Masse moléculaire:460.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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FGFR1 0.631 nM (IC50) |
FGFR2 1.26 nM (IC50) |
FGFR3 0.851 nM (IC50) |
FGFR4 1 nM (IC50) |
Chemical Information
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CAS No. 1431872-18-2
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Masse moléculaire 460.46
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Formule C23H21FN8O2
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SMILES
FC1=C(N(CC2=NC=CN2)C3=NC4=NC(C5=CN(C)N=C5)=CN=C4C=C3)C=C(OC)C=C1OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FGFR-IN-22 Related Classifications
HY-177276 Related Classifications
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