SMYD4 - SET and MYND domain containing 4 Gene

Also Known as ZMYND21

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 114826

About SMYD4

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:1,779,485-1,829,902 (from NCBI)

This gene has 7 transcripts (splice variants), 211 orthologues and 5 paralogues. Ubiquitous expression in ovary (RPKM 3.5), fat (RPKM 3.2) and 25 other tissues.

Summary

Predicted to enable metal ion binding activity and methyltransferase activity. Involved in heart development. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SMYD4 Products (1)

mRNA Protein Name
NM_052928.3 NP_443160.2 SET and MYND domain-containing protein 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
30110327 GOA
Biological Process GO Annotation Evidence Références Source
involved in heart development IMP
IMP: Inferred from mutant phenotype
30110327 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SMYD4 Protein Structure

TPR_11

TPR_11: TPR repeat (68 - 132)

SET

SET: SET domain (244 - 574)

zf-MYND

zf-MYND: MYND finger (296 - 335)

  • 0
  • 200
  • 400
  • 600
  • 804 a.a.
Protein Preferred Names Protein Names

SET and MYND domain-containing protein 4

SMYD4 Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P80896 SMYD4 Antibody (YA671) WB Human
HY-P80896A SMYD4 Antibody (YA671)(PBS only) WB Human
HY-P85590 SMYD4 Antibody (YA5282) WB Human

Related Diseases

Diseases Alias
Shukla-Vernon Syndrome

  • SHUVER
Congenital Contractures Of The Limbs And Face, Hypotonia, And Developmental Delay

  • CLIFAHDD

  • Congenital Limbs-Face Contractures-Hypotonia-Developmental Delay Syndrome

  • Clifahdd Syndrome

  • Doid:0081048

  • Contractures, Limbs And Face, Congenital, Hypotonia, And Developmental Delay
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS13468 SMYD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SMYD4 VGNC VGNC:77752
Rattus norvegicus SMYD4 RGD RGD:1307369
Canis familiaris SMYD4 VGNC VGNC:46582
Mus musculus SMYD4 MGD MGI:2442796
Felis catus SMYD4 VGNC VGNC:65512
Bos taurus SMYD4 VGNC VGNC:35045