SMYD4 Antibody (YA5282)
(Synonyms: KIAA1936; SET and MYND domain containing 4; SET and MYND domain-containing protein 4; SMYD4; SMYD4_HUMAN; ZMYND21.)SMYD4 Antibody (YA5282) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SMYD4.
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Host:
Mouse
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:200 |
Product Details
SMYD4 Antibody (YA5282) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SMYD4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 89 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Purified recombinant human SMYD4 protein fragments expressed in E.coli.
affinity chromatography.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SMYD4 is a Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity. May also act as a histone methyltransferase. Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1[1].
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Subcellular Localization
Nucleus; Cytoplasm
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Subunit
Interacts (via MYND-type zinc finger) with HDAC1
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SwissProt ID
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Synonyms
KIAA1936; SET and MYND domain containing 4; SET and MYND domain-containing protein 4; SMYD4; SMYD4_HUMAN; ZMYND21.
Documentation