SMYD4 Antibody (YA671)

(Synonyms: ZMYND21.)
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Based on 1 Customer Validation

SMYD4 Antibody (YA671) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SMYD4.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Conjugation:
    Non-conjugated

Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

SMYD4 Antibody (YA671) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SMYD4.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 89 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 89 kDa
Species Reactivity Database

Entrez Gene: 114826 Human

SwissProt: Q8IYR2 Human

Immunogen

Synthetic peptide corresponding to Human SMYD4.The exact sequence is proprietary to MCE.

Sensitivity

Endogenous

Purification

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity (PubMed:38438251). May also act as a histone methyltransferase (By similarity). Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1 (By similarity)

  • Subcellular Localization

    Nucleus; Cytoplasm

  • Subunit

    Interacts (via MYND-type zinc finger) with HDAC1

  • SwissProt ID

    Q8IYR2

  • Gene ID
  • Synonyms

    ZMYND21.

  • Research Field

    Cancer

SMYD4 Antibody (YA671) Related Classifications

MOQ
Minimum order quantity
100 mg

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