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Cat. No.: HY-183860

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Pefabloc PL

Pefabloc PL is a plasmin inhibitor with submicromolar-range inhibitory activity against the trypsin-like serine protease plasmin.

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CAS No.: 2131171-67-8
Formule: C₃₁H₃₃N₅O₄S₂
Masse moléculaire:603.75

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pefabloc PL Chemical Structure

CAS No.: 2131171-67-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Pefabloc PL is a plasmin inhibitor with submicromolar-range inhibitory activity against the trypsin-like serine protease plasmin^[1].

In Vitro

Pefabloc PL (compound 70) exerts inhibitory effects against plasmin, uPA and plasma kallikrein^[1].
Pefabloc PL inhibits multiple trypsin-type serine proteases at submicromolar level^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2131171-67-8
Masse moléculaire 603.75
Formule C₃₁H₃₃N₅O₄S₂
SMILES

O=C(N1CC(CCC1)C(NCC2=CC=CS2)=O)[C@@H](NS(=O)(C3=CC4=C(C=CC=C4)C=C3)=O)CC5=CC(C(N)=N)=CC=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Steinmetzer T, et al. Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding. J Med Chem. 2020;63(4):1445-1472. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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