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Art. -Nr.: HY-163342

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Antibacterial agent 190

Antibacterial agent 190 (compound 16) is a antibacterial agent. Antibacterial agent 190 shows antibacterial activity. Antibacterial agent 190 reduces the bacterial burden of the peritoneum and blood.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₃₉H₅₀N₁₀O₄
Molecular Weight:722.88

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Antibacterial agent 190 Chemical Structure

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Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Antibacterial agent 190 (compound 16) is a antibacterial agent. Antibacterial agent 190 shows antibacterial activity. Antibacterial agent 190 reduces the bacterial burden of the peritoneum and blood^[1].

In Vitro

Antibacterial agent 190 shows antibacterial activity with MIC values of 0.12-0.25, 0.03, 0.12, 0.03, 0.12 µg/mL for Staphylococcus aureus USA30, Streptococcus pneumoniae, Enterococcus faecium, Vancomycin-resistant Enterococcus faecium, Linezolid-resistant Enterococcus faecium, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Antibacterial agent 190 (80 mg/kg; s.c.) reduces the bacterial burden of the peritoneum and blood in mouse sepsis/peritonitis infection model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

20 g, 21 NMRI female mice (S. aureus ATCC 25923; i.p.)^[1]
Dosage:

80 mg/kg
Administration:

S.c.
Result:

Reduced the bacterial burden of the peritoneum and blood.

Chemical Information

Molecular Weight 722.88
Formel C₃₉H₅₀N₁₀O₄
SMILES

C[C@@H]1CC[C@]2([C@H]3C)[C@](C(CC2)=O)([H])[C@@]1([C@H](OC(CN4N=NC(C5=CC=C(N=C5)CN6C=NC7=C6N=CN=C7N8CCNCC8)=C4)=O)C[C@](C)([C@H]3O)C=C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Heidtmann CV, et al. Hit-to-Lead Identification and Validation of a Triaromatic Pleuromutilin Antibiotic Candidate. J Med Chem. 2024 Feb 22. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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