2891696-18-5
Chemical Structure
SGK1-IN-3
- CAS. Nr.: 2891696-18-5
- Formula:C23H20Cl2N6O3S
- Molecular Weight:531.41
IUPAC Name: (6R,7R)-7-((Z)-2-(furan-2-yl)-2-((methoxy-d3)imino)acetamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: UKMBVWVIQHGQEM-OAHLLOKOSA-N
SMILES: O=C(C1=CC(C2=CC=C(C=C2)NS(=O)(C3=C(C(Cl)=CC=C3)Cl)=O)=NC4=C1C=NN4)N[C@@H]5CCNC5
Biological Activity: SGK1-IN-3 (Compound 3a) is an ATP-competitive SGK1 inhibitor with an IC50 of <1 nM against hSGK1. SGK1-IN-3 blocks the activity of CDK family members. SGK1-IN-3 is a P-glycoprotein substrate. SGK1-IN-3 can be used for research on osteoarthritis[1].
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SGK1-IN-3 | SGK1-IN-3 (Compound 3a) is an ATP-competitive SGK1 inhibitor with an IC50 of <1 nM against hSGK1. SGK1-IN-3 blocks the activity of CDK family members. SGK1-IN-3 is a P-glycoprotein substrate. SGK1-IN-3 can be used for research on osteoarthritis. | |||||||||||||||||||||
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Keywords
