DBCO-PEG5000-NHS
DBCO-PEG5000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material.
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- Molecular Weight:5000 (Average)
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
DBCO-PEG-NHS is used to synthesize targeting antibodies for constructing a pretargeted and bioorthogonal capture system for cardiac repair[1].
DBCO-PEG-NHS is used to functionalize antibodies and liposomes for constructing radioimmunoliposomes targeting vascular endothelial cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 5000 (Average)
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SMILES
O=C(CCC(NCCOCC(ON1C(CCC1=O)=O)=O)=O)N2C3=CC=CC=C3C#CC4=CC=CC=C4C2.[n]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Li Z, et al. Pretargeting and Bioorthogonal Click Chemistry-Mediated Endogenous Stem Cell Homing for Heart Repair. ACS Nano. 2018;12(12):12193-12200. [Content Brief]
[2]. Hood ED, et al. Vascular Targeting of Radiolabeled Liposomes with Bio-Orthogonally Conjugated Ligands: Single Chain Fragments Provide Higher Specificity than Antibodies. Bioconjug Chem. 2018;29(11):3626-3637. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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