Unc5b - unc-5 netrin receptor B Gene

Also Known as Unc5h2; A630020F16; D10Bwg0792e; 6330415E02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 107449

Summary

Predicted to enable netrin receptor activity. Acts upstream of or within anterior/posterior axon guidance. Predicted to be located in membrane raft. Is expressed in several structures, including brain; forelimb; ganglia; limb bud; and sensory organ. Orthologous to human UNC5B (unc-5 netrin receptor B). [provided by Alliance of Genome Resources, Apr 2022]

Unc5b Products (2)

mRNA Protein Name
NM_001359273.1 NP_001346202.1 netrin receptor UNC5B isoform 2 precursor
NM_029770.3 NP_084046.2 netrin receptor UNC5B isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
21172653 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within anterior/posterior axon guidance IMP
IMP: Inferred from mutant phenotype
18479186 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

netrin receptor UNC5B

  • protein unc-5 homolog 2

  • protein unc-5 homolog B

  • unc5 homolog 2

Unc5b Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
Unc5b Q8K1S3 Ppp2r1b Mus musculus Q7TNP2
Anti Bait CoIP
21172653
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS15472 UNC5B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18193 Unc5b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24667 Unc5b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-P991624 Anti-UNC5B Antibody (YW88) Inhibitor 95.17% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Unc5b NCBI NCBI:219699
Rattus norvegicus Unc5b NCBI NCBI:60630