HSPA9 - Hspa9 heat shock protein family A (Hsp70) member 9 Gene

Also Known as Crp40; PBP74; GRP-75; Hspa9a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291671

Summary

Enables chaperone binding activity; Fibroblast Growth Factor binding activity; and heat shock protein binding activity. Involved in several processes, including cellular response to interleukin-1; response to folic acid; and response to thyroxine. Located in mitochondrion. Biomarker of Parkinsonism and brain ischemia. Human ortholog(s) of this gene implicated in Parkinson's disease and autosomal dominant sideroblastic anemia 4. Orthologous to human HSPA9 (heat shock protein family A (HSP70) member 9). [provided by Alliance of Genome Resources, Apr 2022]

HSPA9 Products (1)

mRNA Protein Name
NM_001100658.2 NP_001094128.2 stress-70 protein, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables fibroblast growth factor binding IPI
IPI: Inferred from physical interaction
10510314 RGD
enables heat shock protein binding IPI
IPI: Inferred from physical interaction
15030183 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9538267 RGD
enables protein-folding chaperone binding IPI
IPI: Inferred from physical interaction
9694873 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in calcium import into the mitochondrion IMP
IMP: Inferred from mutant phenotype
17178908 RGD
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
15621568 RGD
involved in protein autophosphorylation IDA
IDA: Inferred from direct assay
7811387 RGD
involved in response to folic acid IEP
IEP: Inferred from expression pattern
16251605 RGD
involved in response to thyroxine IEP
IEP: Inferred from expression pattern
21563808 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
7901206 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17178908 RGD
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
17178908 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

stress-70 protein, mitochondrial

  • 75 kDa glucose-regulated protein

  • GRP 75

  • catecholamine regulated protein 40

  • heat shock 70 kDa protein 9

  • heat shock 70kDa protein 9A

  • heat shock protein 9

  • heat shock protein family A member 9

  • heat shock protein, A

  • mortalin

  • mtHSP70

  • peptide-binding p

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-152153 GRP78-IN-3 Inhibitor 99.88% Unkown
HY-RS06437 HSPA9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18519 Hspa9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25001 Hspa9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HSPA9 NCBI NCBI:3313