Map6 - microtubule-associated protein 6 Gene

Also Known as Mtap6

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29457

Summary

Enables microtubule binding activity. Involved in axonal transport of mitochondrion; positive regulation of axonogenesis; and regulation of microtubule Cytoskeleton organization. Located in several cellular components, including Golgi apparatus; dendrite; and secretory vesicle. Orthologous to human MAP6 (microtubule associated protein 6). [provided by Alliance of Genome Resources, Apr 2022]

Map6 Products (3)

mRNA Protein Name
NM_001398600.1 NP_001385529.1 microtubule-associated protein 6 isoform 1
NM_001398601.1 NP_001385530.1 microtubule-associated protein 6 isoform 2
NM_001398602.1 NP_001385531.1 microtubule-associated protein 6 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables microtubule binding IDA
IDA: Inferred from direct assay
28521134 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
24357581 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in axonal transport of mitochondrion IMP
IMP: Inferred from mutant phenotype
28521134 RGD
involved in positive regulation of axonogenesis IMP
IMP: Inferred from mutant phenotype
28521134 RGD
involved in regulation of microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
28521134 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
28521134 RGD
located in axon IDA
IDA: Inferred from direct assay
28521134 RGD
located in dendrite IDA
IDA: Inferred from direct assay
28521134 RGD
located in neuron projection IDA
IDA: Inferred from direct assay
28521134 RGD
located in secretory vesicle IDA
IDA: Inferred from direct assay
28521134 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microtubule-associated protein 6

  • 145-kDa STOP

  • MAP-6

  • STOP

  • STOP145

  • microtubule-associated protein 6 homolog

  • stable tubule-only polypeptide

Map6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
Map6 Q63560 Tmem106b Rattus norvegicus Q6AYA5
Density Sedimentation
24357581
Intra
Map6 Q63560 Tmem106b Rattus norvegicus Q6AYA5
Anti Tag CoIP
24357581
Intra
Map6 Q63560 Tmem106b Rattus norvegicus Q6AYA5
IF
24357581
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS08086 MAP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map6 NCBI NCBI:4135