MAP6 - microtubule associated protein 6 Gene

Homo sapiens

Also known as STOP; MTAP6; MAP6-N; N-STOP

Gene ID: 4135 | Gene type: protein coding

About MAP6

Cytogenetic location: 11q13.5 Genomic coordinates (GRCh38): 11:75,586,918-75,669,038 (from NCBI)

This gene has 4 transcripts (splice variants), 267 orthologues and 1 paralogue. Biased expression in brain (RPKM 4.6), testis (RPKM 2.8) and 13 other tissues.

Summary

This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

MAP6 Products(2)

mRNA	Protein	Name
NM_033063.2	NP_149052.1	microtubule-associated protein 6 isoform 1
NM_207577.1	NP_997460.1	microtubule-associated protein 6 isoform 2

MAP6 Protein Structure

STOP

0
200
400
600
813 a.a.

Protein Preferred Names

Protein Names

microtubule-associated protein 6

CTD-2530H12.7

Related Diseases

Diseases

Alias

Cardia Cancer

Ca Cardia - Stomach

Malignant Neoplasm Of Cardia Of Stomach

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Schizophrenia 1

SCZD1	Schizophrenia Susceptibility Locus, Chromosome 5-Related
Schizophrenia 1 With Or Without An Affective Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08086	MAP6 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MAP6	VGNC	VGNC:74640
Canis familiaris	MAP6	VGNC	VGNC:42986
Bos taurus	MAP6	VGNC	VGNC:54448
Mus musculus	MAP6	MGD	MGI:1201690
Felis catus	MAP6	VGNC	VGNC:82020
Rattus norvegicus	MAP6	RGD	RGD:61804