MAP6 - microtubule associated protein 6 Gene

Also Known as STOP; MTAP6; MAP6-N; N-STOP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4135

About MAP6

Cytogenetic location: 11q13.5 Genomic coordinates (GRCh38): 11:75,586,918-75,669,038 (from NCBI)

This gene has 4 transcripts (splice variants), 267 orthologues and 1 paralogue. Biased expression in brain (RPKM 4.6), testis (RPKM 2.8) and 13 other tissues.

Summary

This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

MAP6 Products (2)

mRNA Protein Name
NM_033063.2 NP_149052.1 microtubule-associated protein 6 isoform 1
NM_207577.1 NP_997460.1 microtubule-associated protein 6 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24357581 GOA
Biological Process GO Annotation Evidence References Source
involved in dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
24357581 GOA
involved in lysosome localization IMP
IMP: Inferred from mutant phenotype
24357581 GOA
Cellular Component GO Annotation Evidence References Source
located in microtubule IDA
IDA: Inferred from direct assay
17210638 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
17210638 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAP6 Protein Structure

STOP

STOP: STOP protein (3 - 166)

  • 0
  • 200
  • 400
  • 600
  • 813 a.a.
Protein Preferred Names Protein Names

microtubule-associated protein 6

  • CTD-2530H12.7

Related Diseases

Diseases Alias
Cardia Cancer

  • Ca Cardia - Stomach

  • Malignant Neoplasm Of Cardia Of Stomach
Schizophrenia

  • SCZD

  • Schizophrenia With Or Without An Affective Disorder

  • Schizophrenia 12

  • Schizophrenia, Susceptibility To

  • Schizophrenia-1

  • Dementia Praecox

  • Schizophrenia 1
Schizophrenia 1

  • SCZD1

  • Schizophrenia Susceptibility Locus, Chromosome 5-Related

  • Schizophrenia 1 With Or Without An Affective Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08086 MAP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MAP6 VGNC VGNC:74640
Canis familiaris MAP6 VGNC VGNC:42986
Bos taurus MAP6 VGNC VGNC:54448
Mus musculus MAP6 MGD MGI:1201690
Felis catus MAP6 VGNC VGNC:82020
Rattus norvegicus MAP6 RGD RGD:61804
Others MAP6 NCBI