Map6 - microtubule-associated protein 6 Gene

Rattus norvegicus

Also known as Mtap6

Gene ID: 29457 | Gene type: protein coding

About Map6

Summary

Enables microtubule binding activity. Involved in axonal transport of mitochondrion; positive regulation of axonogenesis; and regulation of microtubule Cytoskeleton organization. Located in several cellular components, including Golgi apparatus; dendrite; and secretory vesicle. Orthologous to human MAP6 (microtubule associated protein 6). [provided by Alliance of Genome Resources, Apr 2022]

Map6 Products(3)

mRNA	Protein	Name
NM_001398600.1	NP_001385529.1	microtubule-associated protein 6 isoform 1
NM_001398601.1	NP_001385530.1	microtubule-associated protein 6 isoform 2
NM_001398602.1	NP_001385531.1	microtubule-associated protein 6 isoform 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables microtubule binding	IDA IDA: Inferred from direct assay	28521134	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	24357581	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in axonal transport of mitochondrion	IMP IMP: Inferred from mutant phenotype	28521134	RGD
involved in positive regulation of axonogenesis	IMP IMP: Inferred from mutant phenotype	28521134	RGD
involved in regulation of microtubule cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	28521134	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in Golgi apparatus	IDA IDA: Inferred from direct assay	28521134	RGD
located in axon	IDA IDA: Inferred from direct assay	28521134	RGD
located in dendrite	IDA IDA: Inferred from direct assay	28521134	RGD
located in neuron projection	IDA IDA: Inferred from direct assay	28521134	RGD
located in secretory vesicle	IDA IDA: Inferred from direct assay	28521134	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

microtubule-associated protein 6

145-kDa STOP	MAP-6
STOP	STOP145
microtubule-associated protein 6 homolog	stable tubule-only polypeptide

Map6 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Map6	Q63560	Tmem106b	Rattus norvegicus	Q6AYA5	Density Sedimentation	24357581
Intra	Map6	Q63560	Tmem106b	Rattus norvegicus	Q6AYA5	Anti Tag CoIP	24357581
Intra	Map6	Q63560	Tmem106b	Rattus norvegicus	Q6AYA5	IF	24357581

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08086	MAP6 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Map6	NCBI	NCBI:4135

Name
Email *

	Sorry, but the email address you supplied was invalid.