Lpcat1 - lysophosphatidylcholine acyltransferase 1 Gene

Also Known as Aytl2; RGD1311599

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361467

Summary

Enables 1-acylglycerol-3-phosphate O-acyltransferase activity and 1-acylglycerophosphocholine O-acyltransferase activity. Predicted to be involved in phosphatidylcholine acyl-chain remodeling and phospholipid biosynthetic process. Predicted to act upstream of or within several processes, including negative regulation of phosphatidylcholine biosynthetic process; positive regulation of protein catabolic process; and surfactant homeostasis. Predicted to be located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and lipid droplet. Orthologous to human LPCAT1 (lysophosphatidylcholine Acyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Lpcat1 Products (1)

mRNA Protein Name
NM_001100735.1 NP_001094205.1 lysophosphatidylcholine acyltransferase 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables 1-acylglycerol-3-phosphate O-acyltransferase activity IDA
IDA: Inferred from direct assay
16864775 RGD
enables 1-acylglycerophosphocholine O-acyltransferase activity IDA
IDA: Inferred from direct assay
16864775 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysophosphatidylcholine acyltransferase 1

  • 1-acylglycerol-3-phosphate O-acyltransferase

  • 1-acylglycerophosphocholine O-acyltransferase

  • 1-alkenylglycerophosphocholine O-acyltransferase

  • 1-alkylglycerophosphocholine O-acetyltransferase

  • LPC acyltransferase 1

  • LPCAT-1

  • acetyl-CoA:lyso-PAF acetyltran

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-W140439 1-Oleoyl-sn-glycero-3-phosphocholine 99.58% Unkown
HY-112825 TSI-01 Inhibitor 98.52% Unkown
HY-RS07764 LPCAT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18199 Lpcat1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24675 Lpcat1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lpcat1 NCBI NCBI:79888