ZCCHC7 - zinc finger CCHC-type containing 7 Gene

Also Known as AIR1; HSPC086

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 84186

About ZCCHC7

This gene has 9 transcripts (splice variants), 203 orthologues and 3 paralogues. Ubiquitous expression in lymph node (RPKM 3.6), testis (RPKM 2.2) and 25 other tissues.

Summary

Enables RNA binding activity. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

ZCCHC7 Products (4)

mRNA	Protein	Name
NM_001289119.2	NP_001276048.1	zinc finger CCHC domain-containing protein 7
NM_001289120.2	NP_001276049.1	zinc finger CCHC domain-containing protein 7
NM_001289121.2	NP_001276050.1	zinc finger CCHC domain-containing protein 7
NM_032226.3	NP_115602.2	zinc finger CCHC domain-containing protein 7

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Verweise	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZCCHC7 Protein Structure

zf-CCHC

0
100
200
300
400
500
543 a.a.

Protein Preferred Names	Protein Names
zinc finger CCHC domain-containing protein 7	TRAMP-like complex RNA-binding factor ZCCHC7

ZCCHC7 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Verweise
Intra	ZCCHC7	Q8N3Z6	q59gp6_human	Homo sapiens	Q59GP6	Y2H Prey Pooling	25416956
Intra	ZCCHC7	Q8N3Z6	q59gp6_human	Homo sapiens	Q59GP6	Y2H Array	25416956
Intra	ZCCHC7	Q8N3Z6	NEK6	Homo sapiens	Q9HC98-4	Validated Y2H	32296183
Intra	ZCCHC7	Q8N3Z6	GIPC2	Homo sapiens	Q8TF65	Validated Y2H	32296183
Intra	ZCCHC7	Q8N3Z6	TRIM41	Homo sapiens	Q8WV44	Validated Y2H	32296183
Intra	ZCCHC7	Q8N3Z6	CARD9	Homo sapiens	Q9H257	Y2H Array	25416956
Intra	ZCCHC7	Q8N3Z6	CARD9	Homo sapiens	Q9H257	Y2H Prey Pooling	25416956
Intra	ZCCHC7	Q8N3Z6	CARD9	Homo sapiens	Q9H257	Validated Y2H	25416956
Intra	ZCCHC7	Q8N3Z6	KIF9	Homo sapiens	Q9HAQ2	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Trichohepatoenteric Syndrome 1	Trichohepatoenteric Syndrome Syndromic Diarrhea Tricho-Hepato-Enteric Syndrome Sd/The Syndromic Diarrhea/Tricho-Hepato-Enteric Syndrome THES1 Phenotypic Diarrhea Thes Phenotypic Diarrhea Of Infancy Diarrhea, Syndromic Diarrhea, Fatal Infantile, With Trichorrhexis Nodosa Intractable Diarrhea With Phenotypic Anomalies Syndromatic Diarrhea Fatal Infantile Diarrhea With Trichorrhexis Nodosa
Pontocerebellar Hypoplasia, Type 1e	Pontocerebellar Hypoplasia Type 1 PCH1E Norman Disease Pch1 Pontocerebellar Hypoplasia With Anterior Horn Cell Disease Pontocerebellar Hypoplasia With Infantile Spinal Muscular Atrophy Pontocerebellar Hypoplasia Type 1e Pontocerebellar Hypoplasia 1e Doid:0112322 Doid:0112330
Pontocerebellar Hypoplasia	Pch Congenital Pontocerebellar Hypoplasia Opch Hypoplasia, Pontocerebellar Pontoneocerebellar Hypoplasia Nonsyndromic Pontocerebellar Hypoplasia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-RS16006	ZCCHC7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ZCCHC7	RGD	RGD:1310467
Canis familiaris	ZCCHC7	VGNC	VGNC:53504
Bos taurus	ZCCHC7	VGNC	VGNC:37122
Macaca mulatta	ZCCHC7	VGNC	VGNC:82088
Felis catus	ZCCHC7	VGNC	VGNC:103010
Mus musculus	ZCCHC7	MGD	MGI:2442912
Others	ZCCHC7	NCBI