Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
183 Results for "
lenalidomide
" in MedChemExpress (MCE) Product Catalog:
Products (183)
183 Results for "lenalidomide" in MCE Product Catalog:
Target:
Forschungsgebiete:
Lenalidomide-6-F is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-6-F can be connected to the ligand for protein by a linker to form PROTAC .
Target:
Forschungsgebiete:
Lenalidomide-I (Compound 72), an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, is used in the recruitment of CRBN protein. Lenalidomide-I can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BET degrader QCA570 (HY-112609) .
Art. -Nr.: HY-132226
CAS. Nr.: 2468780-76-7
Target:
Forschungsgebiete:
Desamino lenalidomide-5-F is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-5-F can be linked to a target protein ligand via a linker to form a PROTAC.
Art. -Nr.: HY-43722
CAS. Nr.: 2093387-36-9
Target:
Forschungsgebiete:
Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC STAT3 degrader SD-36 (HY-129602) .
Art. -Nr.: HY-160241
CAS. Nr.: 2338824-30-7
Forschungsgebiete:
Lenalidomide-C5-acid is the Lenalidomide-based E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Lenalidomide-C5-acid can be used to synthesize PROTACs .
Art. -Nr.: HY-161128
CAS. Nr.: 2624336-86-1
Forschungsgebiete:
Lenalidomide 4'-PEG1-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG1-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
Art. -Nr.: HY-W079257
CAS. Nr.: 2287267-33-6
Target:
Forschungsgebiete:
Desamino lenalidomide-7-F is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-7-F can be linked to a target protein ligand via a linker to form a PROTAC.
Art. -Nr.: HY-W244728
CAS. Nr.: 2291363-98-7
Target:
Forschungsgebiete:
Desamino lenalidomide-pinacolborane is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-pinacolborane can be linked to a target protein ligand via a linker to form a PROTAC.
Art. -Nr.: HY-A0003R
CAS. Nr.: 191732-72-6
Synonyms: CC-5013 (Standard)
Forschungsgebiete:
Lenalidomide (Standard) is the analytical standard of Lenalidomide. This product is intended for research and analytical applications. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells .
Art. -Nr.: HY-122725
CAS. Nr.: 2093388-45-3
Lenalidomide-C5-NH2 is an E3 ligase ligand-linker conjugate. Lenalidomide-C5-NH2 can be coupled to a target protein ligand via a linker to form a PROTAC molecule—such as a PROTAC degrader for MDM2 .
Art. -Nr.: HY-157566
CAS. Nr.: 2520105-60-4
Target:
Forschungsgebiete:
Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride is a functionalized cerebellar ligand for PROTAC development, combining E3 ligand and terminal piperidine for subsequent chemical reactions. A protein degradant with a rigid connector is generated .
Art. -Nr.: HY-161129
CAS. Nr.: 2624336-88-3
Forschungsgebiete:
Lenalidomide 4'-PEG2-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
Art. -Nr.: HY-145461
CAS. Nr.: 1421593-78-3
Synonyms: 5-Hydroxy lenalidomide
Target:
Forschungsgebiete:
Hydroxy lenalidomide (5-Hydroxy lenalidomide) is a metabolite of lenalidomide that is present as a minor component in plasma and excreta, accounting for less than 5% of the total radioactivity, following oral administration of lenalidomide in healthy male subjects.
Target:
Forschungsgebiete:
Lenalidomide-4-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC
Art. -Nr.: HY-W458077
CAS. Nr.: 1416990-10-7
Target:
Forschungsgebiete:
Desamino lenalidomide-7-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-7-OH can be linked to a target protein ligand via a linker to form a PROTAC.
Art. -Nr.: HY-W586326
CAS. Nr.: 2703764-14-9
Target:
Forschungsgebiete:
Desamino lenalidomide-4-COOH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-4-COOH can be linked to a target protein ligand via a linker to form a PROTAC.
Art. -Nr.: HY-W580776
CAS. Nr.: 2639386-82-4
Target:
Forschungsgebiete:
Desamino lenalidomide-cyano is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-cyano can be linked to a target protein ligand via a linker to form a PROTAC.
Art. -Nr.: HY-W586342
CAS. Nr.: 2287259-68-9
Target:
Forschungsgebiete:
Desamino lenalidomide-COOH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-COOH can be linked to a target protein ligand via a linker to form a PROTAC.
Art. -Nr.: HY-W998267
CAS. Nr.: 2698398-71-7
Target:
Forschungsgebiete:
Desamino lenalidomide-Bpin is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-Bpin can be linked to a target protein ligand via a linker to form a PROTAC.
Synonyms: Cereblon ligand 1 hydrochloride; E3 ligase Ligand-Linker Conjugates 32 hydrochloride
Forschungsgebiete:
Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC50s of 0.98 nM and 13.7 nM in inhibition of RS4;11 and MOLM-13 acute leukemia cell lines growth, respectively .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
