FAP-IN-2 TFA
Based on 1 publication(s) in Google Scholar
FAP-IN-2 TFA is an isonitrile-containing fibroblast activation protein (FAP) inhibitor. FAP-IN-2 TFA can be labeled with technetium-99m (99mTc) for targeted tumor SPECT imaging.
For research use only. We do not sell to patients.
- Purity: 99.80%
- Formula: C30H31F11N6O9
- Molecular Weight:828.58
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) FAP-IN-2 TFA
More
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 828.58
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Formula C30H31F11N6O9
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Color Light yellow to yellow
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SMILES
O=C(N1[C@@H](CC(F)(C1)F)C#N)CNC(C2=CC=NC3=C2C=C(OCCCN4CCNCC4)C=C3)=O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Sci Adv
Targeting cancer-associated fibroblasts for real-time intraoperative tumor identification with a spray-on fluorescent probe. [Abstract]2025 Nov 21;11(47):eaeb5810. PMID: 41259533
Solvent & Solubility
DMSO : 250 mg/mL (301.72 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 100 mg/mL (120.69 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 1.2069 mL | 6.0344 mL | 12.0688 mL | 30.1721 mL |
| 5 mM | 0.2414 mL | 1.2069 mL | 2.4138 mL | 6.0344 mL | |
| 10 mM | 0.1207 mL | 0.6034 mL | 1.2069 mL | 3.0172 mL | |
| 15 mM | 0.0805 mL | 0.4023 mL | 0.8046 mL | 2.0115 mL | |
| 20 mM | 0.0603 mL | 0.3017 mL | 0.6034 mL | 1.5086 mL | |
| 25 mM | 0.0483 mL | 0.2414 mL | 0.4828 mL | 1.2069 mL | |
| 30 mM | 0.0402 mL | 0.2011 mL | 0.4023 mL | 1.0057 mL | |
| 40 mM | 0.0302 mL | 0.1509 mL | 0.3017 mL | 0.7543 mL | |
| 50 mM | 0.0241 mL | 0.1207 mL | 0.2414 mL | 0.6034 mL | |
| 60 mM | 0.0201 mL | 0.1006 mL | 0.2011 mL | 0.5029 mL | |
| 80 mM | 0.0151 mL | 0.0754 mL | 0.1509 mL | 0.3772 mL | |
| 100 mM | 0.0121 mL | 0.0603 mL | 0.1207 mL | 0.3017 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.