Antibacterial agent 141
Antibacterial agent 141 (Compound B14) has antibacterial activity against four plant pathogens Xoo, Xac, Psa and Cmm, with an EC50 value of 1.28 μM. Antibacterial agent 141 can inhibit the formation of cell membrane and change cell permeability.
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- CAS No.: 2930013-56-0
- Formule: C23H27ClN2O3
- Masse moléculaire:414.93
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Antibacterial agent 141 significantly induces cell membrane rupture in Xoo bacteria[1].
Antibacterial agent 141 increases bacterial membrane permeability in a concentration-dependent manner in Xoo bacteria[1].
Antibacterial agent 141 damages the cell membrane surface in Xoo bacteria[1].
Antibacterial agent 141 (3.2, 6.4 μM) significantly reduces the expression of ACC, ACP and Fab family genes in Xoo bacteria[1].
Antibacterial agent 141 significantly suppresses the formation of Xoo biofilm with the increase of concentration[1].
Antibacterial agent 141 is low toxic to HepG2 and HK-2 cell[1].
Antibacterial agent 141 (0.64-5.12 μM; 3-30 h) significantly inhibits the growth of Xoo bacteria[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Xoo bacteria
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Concentration:3.2, 6.4 μM
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Incubation Time:
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Result:Significantly reduced the expression of ACC, ACP and Fab family genes in Xoo bacteria.
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Cell Line:Xoo bacteria
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Concentration:0.64, 1.28, 2.56, 5.12 μM
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Incubation Time:3, 6, 9, 12, 15, 18, 21, 24, 27, 30 h
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Result:Had a slight inhibitory effect on bacterial growth with the concentration of 0.64, 1.28, 2.56 μM.
Inhibited the growth of bacteria more obviously when the drug concentration reached 5.12 μM.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2930013-56-0
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Masse moléculaire 414.93
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Formule C23H27ClN2O3
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SMILES
O=C1CC2(OC3=CC=C(C=C13)Cl)CCN(CC2)CC(CNCC4=CC=CC=C4)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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