Ptprs - protein tyrosine phosphatase, receptor type, S Gene

Also Known as Ptprd; Rptpd; Larptp2; Ptpsigma; Ptpsigma.

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25529

Summary

Enables protein tyrosine Phosphatase activity. Involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Is integral component of postsynaptic density membrane and integral component of synaptic vesicle membrane. Is active in glutamatergic synapse. Is integral component of presynaptic membrane. Orthologous to human PTPRS (protein tyrosine Phosphatase receptor type S). [provided by Alliance of Genome Resources, Apr 2022]

Ptprs Products (1)

mRNA Protein Name
NM_019140.3 NP_062013.2 receptor-type tyrosine-protein phosphatase S precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein tyrosine phosphatase activity IDA
IDA: Inferred from direct assay
8068021 RGD
Biological Process GO Annotation Evidence Références Source
involved in presynapse assembly EXP
EXP: Inferred from Experiment
21262467 RGD
involved in presynapse assembly IDA
IDA: Inferred from direct assay
21262467 RGD
involved in presynapse assembly IMP
IMP: Inferred from mutant phenotype
21262467 RGD
involved in regulation of postsynaptic density assembly EXP
EXP: Inferred from Experiment
21262467 RGD
involved in regulation of postsynaptic density assembly IDA
IDA: Inferred from direct assay
21262467 RGD
involved in regulation of postsynaptic density assembly IMP
IMP: Inferred from mutant phenotype
21262467 RGD
involved in synaptic membrane adhesion IDA
IDA: Inferred from direct assay
20139422 RGD
involved in synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
20139422 RGD
Cellular Component GO Annotation Evidence Références Source
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
21262467 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21262467 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21262467 RGD
located in postsynaptic density membrane IDA
IDA: Inferred from direct assay
22519304 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
21262467 RGD
located in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
22519304 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor-type tyrosine-protein phosphatase S

  • LAR-PTP2

  • R-PTP-S

  • R-PTP-sigma

  • leukocyte common antigen-related protein-tyrosine phosphatase 2

  • leukocyte common antigen-related proten-tyrosine phosphatase 2

  • protein tyrosine phosphatase, receptor type, D

  • receptor-type tyrosine-protein phosphatase sig

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS11449 PTPRS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21709 Ptprs Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28227 Ptprs Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptprs NCBI NCBI:5802
Mus musculus Ptprs NCBI NCBI:19280