Antibacterial agent 228
Antibacterial agent 228 (Compound 8) inhibits the mycobacterial ribosome (IC50 for Mycobacterium smegmatis is 2.31 μM) and exhibits antibacterial activity against M. tuberculosis H37Rv (MIC=2 and 0.25 μg/mL for wildtype and Δ1258c mutant), M. abscessus ATCC 19977 (MIC=8 and 8 μg/mL for wildtype and Δ2780c mutant) and M. smegmatis (MIC=8 μg/mL).
For research use only. We do not sell to patients.
- Formula: C26H42FN3O7
- Molecular Weight:527.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 527.63
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Formula C26H42FN3O7
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SMILES
O[C@@H]1[C@@H]2[C@H](O[C@]([C@](O)(CNCCC3=CC=C(F)C=C3)C[C@@H](CCCC)O4)(O)[C@]4([H])O2)[C@@H](NC)[C@@H](O)[C@H]1NC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)