120205-48-3
120205-48-3
Chemical Structure
Monomethyl auristatin E intermediate-1
- CAS No.: 120205-48-3
- Formula:C14H30ClNO3
- Molecular Weight:295.85
IUPAC Name: (3R,4S,5S)-tert-butyl 3-methoxy-5-methyl-4-(methylamino)heptanoate hydrochloride
InChIKey: JRXGCIIOQALIMZ-LWEGJDAASA-N
SMILES: CC[C@H](C)[C@H](NC)[C@H](OC)CC(OC(C)(C)C)=O.Cl
Biological Activity: Monomethyl auristatin E intermediate-1 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
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Monomethyl auristatin E intermediate-1 | 99.47% | Monomethyl auristatin E intermediate-1 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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