Nmnat1 - nicotinamide nucleotide adenylyltransferase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 298653

Summary

Predicted to enable identical protein binding activity; nicotinamide-nucleotide adenylyltransferase activity; and nicotinate-nucleotide adenylyltransferase activity. Involved in negative regulation of apoptotic DNA fragmentation; negative regulation of neuron apoptotic process; and positive regulation of MAPK cascade. Located in cytoplasm and nucleus. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Orthologous to human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nmnat1 Products (1)

mRNA Protein Name
NM_001037556.2 NP_001032645.2 nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
Protein Preferred Names Protein Names

nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

  • nicotinamide mononucleotide adenylyl transferase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W615108B β-Nicotinamide mononucleotide, reduced form disodium 99.55% Unkown
HY-161712 IMPDH-IN-4 Inhibitor 99.76% Unkown
HY-RS09382 NMNAT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18008 Nmnat1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24481 Nmnat1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nmnat1 NCBI NCBI:64802