Ywhag - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma Gene

Also Known as 14-3-3G

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 56010

Summary

Enables receptor tyrosine kinase binding activity. Involved in cellular response to Insulin stimulus. Located in vesicle. Is active in presynapse. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 56. Orthologous to human YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma). [provided by Alliance of Genome Resources, Apr 2022]

Ywhag Products (1)

mRNA Protein Name
NM_019376.2 NP_062249.1 14-3-3 protein gamma

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21454690 RGD
enables receptor tyrosine kinase binding IPI
IPI: Inferred from physical interaction
15604144 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to insulin stimulus IDA
IDA: Inferred from direct assay
21454690 RGD
Cellular Component GO Annotation Evidence References Source
is active in presynapse IDA
IDA: Inferred from direct assay
16982421 RGD
is active in synapse IDA
IDA: Inferred from direct assay
7964746 RGD
located in vesicle IDA
IDA: Inferred from direct assay
21454690 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

14-3-3 protein gamma

  • 14-3-3 protein gamma-subtype

  • 3-monooxygenase/tryptophan 5-monooxgenase activation protein gamma polypeptide

  • tryosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein gamma

  • tryosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein

Ywhag Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Ywhag P61983 LRRK2 Homo sapiens Q5S007
Pull Down
24351927
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15942 YWHAG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22926 Ywhag Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29440 Ywhag Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ywhag NCBI NCBI:7532