2028299-61-6
Chemical Structure
Mal-VC-PAB-EDA-N-Ac-Calicheamicin
- CAS No.: 2028299-61-6
- Formula:C93H128IN11O31S3
- Molecular Weight:2119.17
InChIKey: PKBXPQVZLJRKNL-IBCSIOGOSA-N
SMILES: C[C@H]1O[C@H](C[C@@H]([C@@H]1SC(C(C(C)=C(C(O[C@@H]2O[C@H]([C@@H]([C@H]([C@H]2O)OC)O)C)=C3OC)I)=C3OC)=O)O)ON[C@@H]4[C@@H](C)OC(O[C@@H](C#C/C=C\C#C[C@@]/5(O)CC6=O)C(C5=C/CSSC(C)(CCC(NCCNC(OCC7=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN8C(C=CC8=O)=O)=O)=O)=O)C=C7)=O)=O)C)=C6NC(OC)=O)[C@H](O[C@H]9C[C@H](OC)[C@@H](N(C(C)=O)CC)CO9)[C@H]4O
Biological Activity: Mal-VC-PAB-EDA-N-Ac-Calicheamicin is a Drug-Linker Conjugate for ADC with potent antitumor activity. Mal-VC-PAB-EDA-N-Ac-Calicheamicin consists of ADC toxin Calicheamicin (HY-19609) and a linker. Mal-VC-PAB-EDA-N-Ac-Calicheamicin can be used for synthesis of ADC, PF-06647263 (HY-111965)[1].
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Mal-VC-PAB-EDA-N-Ac-Calicheamicin | Mal-VC-PAB-EDA-N-Ac-Calicheamicin is a Drug-Linker Conjugate for ADC with potent antitumor activity. Mal-VC-PAB-EDA-N-Ac-Calicheamicin consists of ADC toxin Calicheamicin (HY-19609) and a linker. Mal-VC-PAB-EDA-N-Ac-Calicheamicin can be used for synthesis of ADC, PF-06647263 (HY-111965). | |||||||||||||||||||||
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Keywords
