Germacrene B
Germacrene B is a central intermediate in sesquiterpene biosynthesis. Germacrene B has been ascribed a warm, sweet, woody-spicy, geranium-like odour and is an important flavour constituent of lime peel oil. Germacrene B is also one of the main constituents of the essential oils from different plants that have antibacterial activity.
For research use only. We do not sell to patients.
- CAS No.: 15423-57-1
- Formula: C15H24
- Molecular Weight:204.35
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
6.4 μg/mL
Compound: (E,E)-germacr-1(10),4,7(11)-triene
|
Cytotoxicity against human A2780 cells
Cytotoxicity against human A2780 cells
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[PMID: 15165160] |
Chemical Information
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CAS No. 15423-57-1
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Appearance Oil
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Molecular Weight 204.35
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Formula C15H24
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Color Colorless to off-white
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SMILES
C/C(C)=C1C/C=C(C)/CC/C=C(C)/CC\1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
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Data Sheet (271 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
[1]. Xu H, Dickschat JS. Germacrene B - a central intermediate in sesquiterpene biosynthesis. Beilstein J Org Chem. 2023 Feb 20;19:186-203. [Content Brief]
[2]. Figueiredo PLB, Pinto LC, da Costa JS, da Silva ARC, Mourão RHV, Montenegro RC, da Silva JKR, Maia JGS. Composition, antioxidant capacity and cytotoxic activity of Eugenia uniflora L. chemotype-oils from the Amazon. J Ethnopharmacol. 2019 Mar 25;232:30-38. [Content Brief]
[3]. Pereira TS, Machado Esquissato GN, Costa EV, Nogueira PCL, Castro-Prado MAA. Mutagenic and cytostatic activities of the Xylopia laevigata essential oil in human lymphocytes. Nat Prod Res. 2021 May;35(10):1682-1685. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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