330-55-2
Chemical Structure
Linuron
- No. CAS: 330-55-2
- Formula:C9H10Cl2N2O2
- Molecular Weight:249.09
IUPAC Name: 3-(3,4-dichlorophenyl)-1-methoxy-1-methylurea
InChIKey: XKJMBINCVNINCA-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(Cl)C(Cl)=C1)N(OC)C
Biological Activity:
Linuron is a phenylurea herbicide widely used to control the growth of grasses and weeds in various crops and orchards. Linuron acts as a photosystem II inhibitor. It also functions as a competitive androgen receptor (AR) antagonist, with an EC50 of 200 μM and a Ki of 100 μM against rat AR, and an EC50 of 20 μM against human AR. Linuron exhibits reproductive toxicity in animals and acts as an endocrine disruptor[1][2][3][4].\n
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Linuron | 99.88% | Linuron is a phenylurea herbicide widely used to control the growth of grasses and weeds in various crops and orchards. Linuron acts as a photosystem II inhibitor. It also functions as a competitive androgen receptor (AR) antagonist, with an EC50 of 200 μM and a Ki of 100 μM against rat AR, and an EC50 of 20 μM against human AR. Linuron exhibits reproductive toxicity in animals and acts as an endocrine disruptor.\n |
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Linuron (Standard) | ≥98% | Linuron (Standard) is the analytical standard of Linuron. This product is intended for research and analytical applications. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor. | ||||||||||||||||||||
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Linuron-d6 | 99.76% | Linuron-d6 is the deuterium labeled Linuron (HY-B1866). Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor. | ||||||||||||||||||||
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- [1]. Ding H, et al. Reproductive toxicity of linuron following gestational exposure in rats and underlying mechanisms. Toxicol Lett. 2017;266:49-55. [Content Brief]
- [2]. Horemans B, et al. Functional Redundancy of Linuron Degradation in Microbial Communities in Agricultural Soil and Biopurification Systems. Appl Environ Microbiol. 2016;82(9):2843-2853. Published 2016 Apr 18. [Content Brief]
- [3]. Lambright C, et al. Cellular and molecular mechanisms of action of linuron: an antiandrogenic herbicide that produces reproductive malformations in male rats. Toxicol Sci. 2000;56(2):389-399. [Content Brief]
- [4]. Magnucka EG, et al. Various effects of the photosystem II--inhibiting herbicides on 5-n-alkylresorcinol accumulation in rye seedlings. Pestic Biochem Physiol. 2014;116:56-62. [Content Brief]
Keywords
