Ppia - peptidylprolyl isomerase A Gene

Also Known as CYCA; CyP-A

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25518

Summary

Enables cyclosporin A binding activity. Involved in negative regulation of phosphoprotein Phosphatase activity. Predicted to be located in cytosol; extracellular region; and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Used to study epilepsy. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A). [provided by Alliance of Genome Resources, Apr 2022]

Ppia Products (1)

mRNA Protein Name
NM_017101.1 NP_058797.1 peptidyl-prolyl cis-trans isomerase A

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Referencias Source
enables cyclosporin A binding IDA
IDA: Inferred from direct assay
19832699 RGD
Biological Process GO Annotation Evidence Referencias Source
involved in negative regulation of calcineurin-mediated signaling IDA
IDA: Inferred from direct assay
19832699 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase A

  • PPIase A

  • cyclophilin A

  • cyclosporin A-binding protein

  • p1B15

  • p31

  • rotamase A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-172209 PPIA-IN-1 96.90% Unkown
HY-RS10946 PPIA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18045 Ppia Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24519 Ppia Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppia NCBI NCBI:5478
Mus musculus Ppia NCBI NCBI:268373