Ppia - peptidylprolyl isomerase A Gene

Also Known as Cphn; CypA; SP18; CyP-18

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268373

Summary

Enables Integrin binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in platelet aggregation. Acts upstream of or within neuron differentiation. Located in extracellular space and myelin sheath. Is expressed in several structures, including early conceptus; gonad; hemolymphoid system gland; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A). [provided by Alliance of Genome Resources, Apr 2022]

Ppia Products (1)

mRNA Protein Name
NM_008907.2 NP_032933.1 peptidyl-prolyl cis-trans isomerase A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables integrin binding IDA
IDA: Inferred from direct assay
24429998 MGI
enables peptidyl-prolyl cis-trans isomerase activity IMP
IMP: Inferred from mutant phenotype
24429998 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16352598 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within neuron differentiation IMP
IMP: Inferred from mutant phenotype
16352598 MGI
involved in platelet activation IMP
IMP: Inferred from mutant phenotype
24429998 MGI
involved in platelet aggregation IMP
IMP: Inferred from mutant phenotype
24429998 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
29921611 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase A

  • PPIase A

  • cyclophilin A

  • cyclosporin A-binding protein

  • rotamase A

Recombinant Ppia Proteins

Cat. No. Product Name Accession Purity
HY-P74212 Cyclophilin A Protein, Mouse (His) P17742/NP_032933.1 (M1-L164) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P70007A Cyclophilin A Protein, Mouse P17742 (M1-L164) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-172209 PPIA-IN-1 96.90% Unkown
HY-RS10946 PPIA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18045 Ppia Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24519 Ppia Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppia NCBI NCBI:5478