Psip1 - PC4 and SRSF1 interacting protein 1 Gene

Also Known as Ledgf; Psip2; SBP75

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 313323

Summary

Enables supercoiled DNA binding activity. Predicted to be involved in several processes, including mRNA 5'-splice site recognition; positive regulation of transcription by RNA polymerase II; and response to heat. Located in heterochromatin and transcriptionally active chromatin. Orthologous to human PSIP1 (PC4 and SFRS1 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Psip1 Products (1)

mRNA	Protein	Name
NM_175765.2	NP_786941.1	PC4 and SFRS1-interacting protein

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Referencias	Source
enables supercoiled DNA binding	IDA IDA: Inferred from direct assay	21345933	RGD

Cellular Component GO Annotation	Evidence	Referencias	Source
located in euchromatin	IDA IDA: Inferred from direct assay	21345933	RGD
located in heterochromatin	IDA IDA: Inferred from direct assay	21345933	RGD
NOT located in nucleolus	IDA IDA: Inferred from direct assay	21345933	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
PC4 and SFRS1-interacting protein	PC4 and SFRS1 interacting protein 1 PC4 and SFRS1 interacting protein 2 lens epithelium-derived growth factor supercoiled DNA binding protein 75

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-18601	(±)-BI-D	Inhibitor	98.06%	Unkown
HY-W023758	HDGFRP2/PSIP1-IN-1		99.50%	Unkown
HY-RS11289	PSIP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22744	Psip1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Psip1	NCBI	NCBI:11168