ST4070
ST4070 is a potent, orally active, and selective reversible fatty acid amide hydrolase (FAAH) inhibitor. ST4070 increases endocannabinoid (eCB) brain levels and counteracts neuropathic pain in animal models. ST4070 enhances the endogenous eCB tone in specific brain regions engaged in emotional control, and induces remarkable anxiolytic-like behaviours in rodents. ST4070 can be used for neuropathic pain and anxiety disorders research.
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- No. CAS: 1186236-75-8
- Fòrmula: C20H21NO2
- Peso molecular:307.39
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Chemical Information
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No. CAS 1186236-75-8
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Peso molecular 307.39
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Fòrmula C20H21NO2
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SMILES
O=C(N1CCCCC1)OC(C2=CC=C(C3=CC=CC=C3)C=C2)=C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Costanzo MJ, et al. Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2114-21. [Content Brief]
[2]. Marco EM, et al. Potential Therapeutic Value of a Novel FAAH Inhibitor for the Treatment of Anxiety. PLoS One. 2015 Sep 11;10(9):e0137034. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)