TUBD1 - tubulin delta 1 Gene

Also Known as TUBD

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 51174

About TUBD1

Cytogenetic location: 17q23.1 Genomic coordinates (GRCh38): 17:59,859,479-59,892,943 (from NCBI)

This gene has 16 transcripts (splice variants), 204 orthologues and 23 paralogues. Ubiquitous expression in esophagus (RPKM 3.8), thyroid (RPKM 3.7) and 25 other tissues.

Summary

Predicted to enable GTP binding activity. Predicted to be a structural constituent of Cytoskeleton. Predicted to be involved in microtubule Cytoskeleton organization; mitotic cell cycle; and positive regulation of smoothened signaling pathway. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TUBD1 Products (6)

mRNA	Protein	Name
NM_001193609.2	NP_001180538.1	tubulin delta chain isoform 2
NM_001193610.2	NP_001180539.1	tubulin delta chain isoform 3
NM_001193611.2	NP_001180540.1	tubulin delta chain isoform 4
NM_001193612.2	NP_001180541.1	tubulin delta chain isoform 5
NM_001193613.2	NP_001180542.1	tubulin delta chain isoform 6
NM_016261.4	NP_057345.2	tubulin delta chain isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	33961781	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TUBD1 Protein Structure

Tubulin

0
100
200
300
400
453 a.a.

Protein Preferred Names	Protein Names
tubulin delta chain	delta-tubulin

TUBD1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	TUBD1	Q9UJT1	CCT6B	Homo sapiens	Q92526	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

TUBD1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P83669	delta Tubulin Antibody	WB, IHC-P	Human, Mouse

Related Diseases

Diseases	Alias
Ciliary Dyskinesia, Primary, 27	Primary Ciliary Dyskinesia 27 CILD27 Ciliary Dyskinesia, Primary, 27, Without Situs Inversus Primary Ciliary Dyskinesia 27 Without Situs Inversus Primary Ciliary Dyskinesia 27 With Or Without Situs Inversus Dyskinesia, Ciliary, Primary, 27
Atrial Septal Defect 6	ASD6 Atrial Heart Septal Defect 6 Septal Defect, Atrial, Type 6
Orofaciodigital Syndrome Ix	OFD9 Orofaciodigital Syndrome With Retinal Abnormalities Oral-Facial-Digital Syndrome With Retinal Abnormalities Orofaciodigital Syndrome 9 Oral-Facial-Digital Syndrome Type 9 Ofds Ix Oral-Facial-Digital Syndrome, Type Ix Ofd Syndrome 9 Ofds 9 Oral Facial Digital Syndrome 9 Oral Facial Digital Syndrome Type 9 Orofaciodigital Syndrome Type 9 Orofaciodigital Syndrome, Type Ix
Seckel Syndrome 7	SCKL7 Microcephalic Primordial Dwarfism, Dauber Type Seckel Syndrome, Type 7
Retinitis Pigmentosa 83	RP83 Retinitis Pigmentosa, Type 83
Weaver Syndrome	Wss Weaver-Smith Syndrome WVS Weaver-Like Syndrome Weaver-Williams Syndrome Camptodactyly-Overgrowth-Unusual Facies Syndrome Camptodactyly - Overgrowth - Unusual Facies Ezh2 Related Overgrowth Overgrowth Syndrome With Accelerated Skeletal Maturation, Unusual Facies, And Camptodactyly Weaver Smith Syndrome Weaver Like Syndrome Weaver Williams Syndrome Camptodactyly-Overgrowth-Unusual Facies Weaver Syndrome 1 Weaver Syndrome 2 Wvs1 Wvs2
Primary Ciliary Dyskinesia	Immotile Cilia Syndrome Kartagener Syndrome Dextrocardia Bronchiectasis And Sinusitis Pcd Ciliary Motility Disorders Ciliary Motility Disorder Immotile Ciliary Syndrome Ciliary Dyskinesia Primary Ics Polynesian Bronchiectasis Dextrocardia-Bronchiectasis-Sinusitis Syndrome Immotile Cilia Syndrome, Kartagener Type Primary Ciliary Dyskinesia And Situs Inversus Primary Ciliary Dyskinesia, Kartagener Type Siewert Syndrome Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15259	TUBD1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TUBD1	VGNC	VGNC:66702
Rattus norvegicus	TUBD1	RGD	RGD:1311967
Macaca mulatta	TUBD1	VGNC	VGNC:79052
Mus musculus	TUBD1	MGD	MGI:1891826
Canis familiaris	TUBD1	VGNC	VGNC:47992
Bos taurus	TUBD1	VGNC	VGNC:36510
Others	TUBD1	NCBI