Dasatinib carbaldehyde
Based on 1 Customer Validation
Dasatinib carbaldehyde (BMS-354825 carbaldehyde), the Dasatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER .
For research use only. We do not sell to patients.
- Purity: 98.53%
- CAS No.: 2112837-79-1
- Formula: C21H22ClN7O2S
- Molecular Weight:471.96
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2112837-79-1
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Appearance Solid
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Molecular Weight 471.96
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Formula C21H22ClN7O2S
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Color White to off-white
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SMILES
CC1=C(NC(C2=CN=C(NC3=CC(N4CCN(C=O)CC4)=NC(C)=N3)S2)=O)C(Cl)=CC=C1
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Synonyms
BMS-354825 carbaldehyde; PROTAC ABL binding moiety 4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 33.33 mg/mL (70.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1188 mL | 10.5941 mL | 21.1882 mL | 52.9706 mL |
| 5 mM | 0.4238 mL | 2.1188 mL | 4.2376 mL | 10.5941 mL | |
| 10 mM | 0.2119 mL | 1.0594 mL | 2.1188 mL | 5.2971 mL | |
| 15 mM | 0.1413 mL | 0.7063 mL | 1.4125 mL | 3.5314 mL | |
| 20 mM | 0.1059 mL | 0.5297 mL | 1.0594 mL | 2.6485 mL | |
| 25 mM | 0.0848 mL | 0.4238 mL | 0.8475 mL | 2.1188 mL | |
| 30 mM | 0.0706 mL | 0.3531 mL | 0.7063 mL | 1.7657 mL | |
| 40 mM | 0.0530 mL | 0.2649 mL | 0.5297 mL | 1.3243 mL | |
| 50 mM | 0.0424 mL | 0.2119 mL | 0.4238 mL | 1.0594 mL | |
| 60 mM | 0.0353 mL | 0.1766 mL | 0.3531 mL | 0.8828 mL |
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