LAD1 - ladinin 1 Gene

Also Known as LadA

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3898

About LAD1

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:201,380,833-201,399,324 (from NCBI)

This gene has 7 transcripts (splice variants) and 115 orthologues. Biased expression in esophagus (RPKM 94.2), skin (RPKM 74.3) and 10 other tissues.

Summary

The protein encoded by this gene may be an anchoring filament that is a component of basement membranes. It may contribute to the stability of the association of the epithelial layers with the underlying mesenchyme. [provided by RefSeq, Jul 2008]

LAD1 Products (1)

mRNA Protein Name
NM_005558.4 NP_005549.2 ladinin-1
Protein Preferred Names Protein Names

ladinin-1

  • lad-1

Related Diseases

Diseases Alias
Epidermolysis Bullosa Acquisita

  • Acquired Epidermolysis Bullosa

  • Eb Acquisita

  • Eba

  • Eba - [Epidermolysis Bullosa Acquisita]
Cicatricial Pemphigoid

  • Mucous Membrane Pemphigoid

  • Ocular Pemphigoid

  • Benign Mucous Membrane Pemphigoid

  • Benign Mucous Membrane Pemphigoid With Ocular Involvement

  • Benign Mucosal Pemphigoid

  • Pemphigoid, Benign Mucous Membrane

  • Cicatricial Pemphigoid With Ocular Involvement

  • Ocular Pemphigus

  • Cicatricial Pemphigoid Disease

  • Mucosal Pemphigoid

  • Mucosynechial Pemphigoid

  • Pemphigoid Cicatricial

  • Cicatricial Pemphigoid Involving The Eye

  • Ocular Cicatricial Pemphigoid
Bullous Pemphigoid

  • Benign Pemphigus

  • Senile Dermatitis Herpetiformis

  • Old Age Pemphigus

  • Parapemphigus

  • Pemphigoid

  • Pemphigoid Bullous

  • Pemphigoid, Bullous
Epidermolysis Bullosa, Junctional 4, Intermediate

  • Gabeb

  • JEB4

  • Epidermolysis Bullosa, Junctional 4, Non-Herlitz Type

  • Epidermolysis Bullosa, Generalized Atrophic Benign

  • Epidermolysis Bullosa, Junctional, Localisata Variant
Pemphigus Gestationis
Pyloric Atresia
Epidermolysis Bullosa

  • Acantholysis Bullosa

  • Eb
Alzheimer Disease 18

  • AD18

  • Alzheimer'S Disease 18

  • Alzheimer Disease 18, Late-Onset

  • Alzheimer Disease 18, Susceptibility To

  • Alzheimer'S Disease 18, Late Onset

  • Alzheimer Disease 18 Late-Onset

  • Alzheimer Disease, Susceptibility To, Type 18
Junctional Epidermolysis Bullosa

  • Epidermolysis Bullosa, Junctional

  • Jeb

  • Epidermolysis Bullosa Atrophicans

  • Congenital Junctional Epidermolysis Bullosa

  • Epidermolysis Bullosa Junctional

  • Junctional Eb - [Epidermolysis Bullosa]

  • Jeb - [Junctional Epidermolysis Bullosa]

  • Lucidolytic Epidermolysis Bullosa
Skin Disease

  • Skin Diseases

  • Genodermatosis

  • Abnormality Of The Skin

  • Skin Diseases, Genetic

  • Skin And Subcutaneous Tissue Disease

  • Dermatologic Disorders
Myasthenic Syndrome, Congenital, 5

  • Endplate Acetylcholinesterase Deficiency

  • Congenital Myasthenic Syndrome 5

  • CMS5

  • Ead

  • Engel Congenital Myasthenic Syndrome

  • Myasthenic Syndrome, Congenital, Engel Type

  • Cms Ic

  • Congenital Myasthenic Syndrome Type Ic

  • Congenital Myasthenic Syndrome Type Ic, Formerly

  • Cms1c, Formerly

  • Cms Ic, Formerly

  • Congenital Myasthenic Syndrome Engel Type

  • End Plate Acetylcholinesterase Deficiency

  • Synaptic Congenital Myasthenic Syndromes

  • Cms1c

  • Cmse

  • Congenital Myasthenic Syndrome Type 1c

  • End-Plate Acetylcholinesterase Deficiency

  • Myasthenic Syndrome, Congenital, Type 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02967 COL17A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07491 LAD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-176012 1S-LSD / Unkown
HY-RS18038 Lad1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24512 Lad1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus LAD1 MGD MGI:109343
Felis catus LAD1 VGNC VGNC:67999
Bos taurus LAD1 VGNC VGNC:30766
Rattus norvegicus LAD1 RGD RGD:1310652
Canis familiaris LAD1 VGNC VGNC:42561
Others LAD1 NCBI