Dis3 - DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Gene
Also Known as 2810028N01Rik
Species: Mus musculus
Summary
Predicted to enable 3'-5'-exoribonuclease activity; Endonuclease activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in CUT catabolic process and rRNA catabolic process. Predicted to act upstream of or within rRNA processing. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is expressed in renal cortex; telencephalon ventricular layer; and thymus primordium. Orthologous to human DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease). [provided by Alliance of Genome Resources, Apr 2022]
Dis3 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001360050.1 | NP_001346979.1 | exosome complex exonuclease RRP44 isoform 2 |
| NM_001360051.1 | NP_001346980.1 | exosome complex exonuclease RRP44 isoform 3 |
| NM_028315.2 | NP_082591.2 | exosome complex exonuclease RRP44 isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
exosome complex exonuclease RRP44 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-171498 | gDIS3-13 | Inducer | 96.75% | Unkown |
| HY-RS03778 | DIS3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS03779 | DIS3L Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS03780 | DIS3L2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-173081 | 4"-(2-(p-Chlorophenyl)acetoxyl)spiramycin | Inhibitor | / | Unkown |
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