4"-(2-(p-Chlorophenyl)acetoxyl)spiramycin
4"-(2-(p-Chlorophenyl)acetoxyl)spiramycin (Compound 2d) is a broad-spectrum anti-coronaviral agent via targeting frameshifting element (FSE). 4"-(2-(p-Chlorophenyl)acetoxyl)spiramycin inhibits HCoV-OC43 and HCoV-229E with EC50 values of 0.85 μM and 1.45 μM. 4"-(2-(p-Chlorophenyl)acetoxyl)spiramycin shows a dual-target mechanism that acts on both viral FSE RNA and host DIS3L2.
For research use only. We do not sell to patients.
- Formula: C51H79ClN2O15
- Molecular Weight:995.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 995.63
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Formula C51H79ClN2O15
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SMILES
O=C1O[C@H](C)C/C=C/C=C/[C@H](O[C@@H]2O[C@H](C)[C@@H](N(C)C)CC2)[C@H](C)C[C@H](CC=O)[C@H](OC3[C@H](O)[C@@H](N(C)C)[C@H](O[C@@H]4O[C@@H](C)[C@H](OC(CC5=CC=C(Cl)C=C5)=O)[C@@](O)(C)C4)[C@H](C)O3)[C@@H](OC)[C@H](O)C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)