VDR agonist 2
VDR agonist 2 (compound 16i) is a VDR (vitamin D receptor) agonist that can effectively inhibit TGF-β1-induced activation of hepatic stellate cells (HSC). VDR agonist 2 has significant anti-hepatic fibrosis effects both in vitro and in vivo.
For research use only. We do not sell to patients.
- CAS No.: 3052323-55-1
- Formula: C20H21F3O3
- Molecular Weight:366.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
VDR[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LX-2 | IC50 |
>30 μM
Compound: 16i
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Cytotoxicity against human LX-2 cells by CCK-8 assay
Cytotoxicity against human LX-2 cells by CCK-8 assay
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[PMID: 37406383] |
Chemical Information
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CAS No. 3052323-55-1
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Molecular Weight 366.37
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Formula C20H21F3O3
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SMILES
FC(F)(CCCOC1=CC=C(/C=C/C2=CC=C(C(CO)=C2)CO)C=C1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VDR agonist 2 Related Classifications
HY-149899 Related Classifications
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