1-Adamantanol
Based on 1 Customer Validation
1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.64%
- CAS 番号: 768-95-6
- 分子式: C10H16O
- 分子量:152.24
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Oocyte | IC50 |
20 μM
Compound: 5
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Inhibition of Influenza A Virus M2 proton channel expressed in Xenopus laevis oocytes after 2 mins by two-electrode patch clamp assay
Inhibition of Influenza A Virus M2 proton channel expressed in Xenopus laevis oocytes after 2 mins by two-electrode patch clamp assay
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[PMID: 21691418] |
1-Adamantanol undergoes regioselective hydroxylation to form 1,3-adamantanediol with a conversion rate of 85%, while producing 1,4-adamantanediol as a byproduct accounting for 15% after incubation with the growth culture of Streptomyces sp. SA8 at 25 °C for 120 h[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 768-95-6
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性状 Solid
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分子量 152.24
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分子式 C10H16O
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Color White to off-white
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SMILES
OC12C[C@H]3C[C@@H](C2)C[C@@H](C1)C3
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別名
Tricyclo[3.3.1.1~3,7~]decan-1-ol
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (328.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (604 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.5686 mL | 32.8429 mL | 65.6858 mL | 164.2144 mL |
| 5 mM | 1.3137 mL | 6.5686 mL | 13.1372 mL | 32.8429 mL | |
| 10 mM | 0.6569 mL | 3.2843 mL | 6.5686 mL | 16.4214 mL | |
| 15 mM | 0.4379 mL | 2.1895 mL | 4.3791 mL | 10.9476 mL | |
| 20 mM | 0.3284 mL | 1.6421 mL | 3.2843 mL | 8.2107 mL | |
| 25 mM | 0.2627 mL | 1.3137 mL | 2.6274 mL | 6.5686 mL | |
| 30 mM | 0.2190 mL | 1.0948 mL | 2.1895 mL | 5.4738 mL | |
| 40 mM | 0.1642 mL | 0.8211 mL | 1.6421 mL | 4.1054 mL | |
| 50 mM | 0.1314 mL | 0.6569 mL | 1.3137 mL | 3.2843 mL | |
| 60 mM | 0.1095 mL | 0.5474 mL | 1.0948 mL | 2.7369 mL | |
| 80 mM | 0.0821 mL | 0.4105 mL | 0.8211 mL | 2.0527 mL | |
| 100 mM | 0.0657 mL | 0.3284 mL | 0.6569 mL | 1.6421 mL |
1-Adamantanol 関連分類
HY-Y0531 関連分類
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- 1-Adamantanol
- 768-95-6
- Tricyclo[3.3.1.1~3,7~]decan-1-ol
- Drug Intermediate
- Bacterial
- 1-adOH-hydroxylating enzyme
- regio-selective hydroxylation
- hydroxylation activity
- 1,3-adamantanediol
- photoresist layer material
- Streptomyces sp. SA8
- acrylic ester derivative
- 1,4-adamantanediol
- growing culture broth
- resting cells
- Inhibitor
- inhibitor
- inhibit