Antibacterial agent 12
Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria.
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- CAS 番号: 2382921-99-3
- 分子式: C22H24FN5O5S
- 分子量:489.52
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>25 μM
Compound: 14a-7
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 31654879] |
Antibacterial agent 12 (compound 14a-7) exhibits a MIC value of 0.125 μg/mL against S.aureus[1].
Antibacterial agent 12 (compound 14a-7) is stable in human liver microsome. Antibacterial agent 12 exhibits lower inhibitory activity against human MAO-A compared to Linezolid[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2382921-99-3
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分子量 489.52
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分子式 C22H24FN5O5S
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SMILES
CC(NC[C@H]1CN(C2=CC=C(C3=CC=C(/C=N/N4CCS(CC4)(=O)=O)N=C3)C(F)=C2)C(O1)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)