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製品番号: HY-184226

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ASAP-0031651

ASAP-0031651 is an orally active inhibitor of Zika virus NS2B-NS3 protease. ASAP-0031651 binds the active site of virus NS2B-NS3 protease to inhibit its function. ASAP-0031651 exerts antiviral activity against Zika virus. ASAP-0031651 can be used for the research of virus infection.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₂₀H₂₀F₅N₃O
分子量:413.38

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

ASAP-0031651 構造式

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

ASAP-0031651 potently inhibits ZIKV NS2B-NS3 protease with a K_i of 7.8 nM^[1].
ASAP-0031651 inhibits ZIKV replication in VeroE6 cells with an EC₅₀ of 0.45 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

分子量 413.38
分子式 C₂₀H₂₀F₅N₃O
SMILES

CC1=CC(C(C(NCC(F)F)=O)NC2=CC(CNC3)=C3C=C2)=CC(C(F)(F)F)=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Kenton NT, et al. Discovery of orally bioavailable Zika and West Nile Virus antiviral compounds targeting the NS2B-NS3 protease. bioRxiv [Preprint]. 2025 Jun 20:2025.06.19.660642. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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