3077842-39-5
3077842-39-5
Chemical Structure
Cathepsin L-IN-6
- CAS 番号: 3077842-39-5
- Formula:C24H23FN4O2
- Molecular Weight:418.46
InChIKey: GLXGZUZPDNUFEQ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C=C1)F)NCCCCCN2C=CC3=C(N=CN=C32)OC4=CC=CC=C4
Biological Activity: Cathepsin L-IN-6 (Compound 6a) is a selective cathepsin L inhibitor with an IC50 of 0.021 μM. Cathepsin L-IN-6 suppresses cathepsin L activity by directly binding to cathepsin L. Cathepsin L-IN-6 inhibits IL-6 and IL-8. Cathepsin L-IN-6 shows a high anti-inflammatory activity. Cathepsin L-IN-6 can be used in the research of acute lung injury[1].
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Cathepsin L-IN-6 | Cathepsin L-IN-6 (Compound 6a) is a selective cathepsin L inhibitor with an IC50 of 0.021 μM. Cathepsin L-IN-6 suppresses cathepsin L activity by directly binding to cathepsin L. Cathepsin L-IN-6 inhibits IL-6 and IL-8. Cathepsin L-IN-6 shows a high anti-inflammatory activity. Cathepsin L-IN-6 can be used in the research of acute lung injury. | |||||||||||||||||||||
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References
Keywords
