Dasatinib derivative 1
Based on 1 Customer Validation
Dasatinib derivative 1 (2e) effectively releases NO and increases the concentration of 3′,5′-cyclic guanosine monophosphate, as well as maintains senolytic activity. Dasatinib derivative 1 (2e) can be used in the research for chronic ocular hypertension (COHT) glaucoma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.74%
- CAS 番号: 3079237-53-6
- 分子式: C41H54ClN9O20S5
- 分子量:1188.69
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
化学情報
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CAS 番号 3079237-53-6
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性状 Solid
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分子量 1188.69
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分子式 C41H54ClN9O20S5
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Color White to off-white
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SMILES
O=S(C1=[N+](ON=C1OCCOCCOC(CCC(OCCN2CCN(CC2)C3=NC(C)=NC(NC4=NC=C(S4)C(NC5=C(C=CC=C5Cl)C)=O)=C3)=O)=O)[O-])(C6=CC=CC=C6)=O.OS(=O)(C)=O.OS(=O)(C)=O.OS(=O)(C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 50 mg/mL (42.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8413 mL | 4.2063 mL | 8.4126 mL | 21.0316 mL |
| 5 mM | 0.1683 mL | 0.8413 mL | 1.6825 mL | 4.2063 mL | |
| 10 mM | 0.0841 mL | 0.4206 mL | 0.8413 mL | 2.1032 mL | |
| 15 mM | 0.0561 mL | 0.2804 mL | 0.5608 mL | 1.4021 mL | |
| 20 mM | 0.0421 mL | 0.2103 mL | 0.4206 mL | 1.0516 mL | |
| 25 mM | 0.0337 mL | 0.1683 mL | 0.3365 mL | 0.8413 mL | |
| 30 mM | 0.0280 mL | 0.1402 mL | 0.2804 mL | 0.7011 mL | |
| 40 mM | 0.0210 mL | 0.1052 mL | 0.2103 mL | 0.5258 mL |