Ninj1 - ninjurin 1 Gene

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 18081

Summary

Enables cell-cell adhesion mediator activity and lipopolysaccharide binding activity. Involved in several processes, including leukocyte chemotaxis; pericyte cell migration; and positive regulation of osteoclast development. Acts upstream of or within hyaloid vascular plexus regression and positive regulation of cell-matrix adhesion. Located in extracellular region; filopodium membrane; and synaptic membrane. Is integral component of plasma membrane. Is expressed in several structures, including body cavity or lining; central nervous system; eye; genitourinary system; and vertebral axis musculature. Orthologous to human NINJ1 (ninjurin 1). [provided by Alliance of Genome Resources, Apr 2022]

Ninj1 Products (1)

mRNA Protein Name
NM_013610.3 NP_038638.1 ninjurin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables cell adhesion mediator activity IDA
IDA: Inferred from direct assay
24347169 MGI
enables cell-cell adhesion mediator activity IMP
IMP: Inferred from mutant phenotype
25766274 MGI
enables lipopolysaccharide binding IDA
IDA: Inferred from direct assay
26677008 MGI
enables membrane destabilizing activity IDA
IDA: Inferred from direct assay
33472215 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in cell adhesion IDA
IDA: Inferred from direct assay
24917672 MGI
involved in cell adhesion IMP
IMP: Inferred from mutant phenotype
24347169 MGI
involved in cellular hyperosmotic response IDA
IDA: Inferred from direct assay
37980412 MGI
involved in chemotaxis IDA
IDA: Inferred from direct assay
23142597 MGI
involved in cytolysis IDA
IDA: Inferred from direct assay
33472215 MGI
involved in ferroptosis IDA
IDA: Inferred from direct assay
38396301 MGI
involved in heterotypic cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
25766274 MGI
acts upstream of or within hyaloid vascular plexus regression IMP
IMP: Inferred from mutant phenotype
19557008 MGI
involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
24347169 MGI
involved in leukocyte chemotaxis involved in inflammatory response IDA
IDA: Inferred from direct assay
24917672 MGI
involved in leukocyte chemotaxis involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
30510259 MGI
involved in macrophage chemotaxis IDA
IDA: Inferred from direct assay
24917672 MGI
involved in muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
31091274 MGI
involved in pericyte cell migration IMP
IMP: Inferred from mutant phenotype
25766274 MGI
acts upstream of or within positive regulation of cell-matrix adhesion IMP
IMP: Inferred from mutant phenotype
19557008 MGI
involved in positive regulation of inflammatory response IDA
IDA: Inferred from direct assay
26677008 MGI
involved in positive regulation of osteoclast development IMP
IMP: Inferred from mutant phenotype
30700695 MGI
involved in positive regulation of toll-like receptor 4 signaling pathway IDA
IDA: Inferred from direct assay
25860173 MGI
involved in programmed necrotic cell death IDA
IDA: Inferred from direct assay
37980412 MGI
involved in protein homooligomerization IDA
IDA: Inferred from direct assay
24917672 MGI
involved in pyroptotic cell death IDA
IDA: Inferred from direct assay
36468682 MGI
involved in regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
25766274 MGI
involved in regulation of monocyte chemotaxis IMP
IMP: Inferred from mutant phenotype
32883094 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in extracellular region IDA
IDA: Inferred from direct assay
23142597 MGI
located in filopodium membrane IDA
IDA: Inferred from direct assay
24917672 MGI
is active in plasma membrane IDA
IDA: Inferred from direct assay
38396301 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
27815839 MGI
located in synaptic membrane IDA
IDA: Inferred from direct assay
27815839 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ninjurin-1

  • nerve injury-induced protein 1

Related Agents

  • Approval

Approval

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Rare Diseases
HY-Y0966 Glycine Inhibitor 99.93% Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Ninj1 NCBI NCBI:4814
Rattus norvegicus Ninj1 NCBI NCBI:25338