NINJ1 - ninjurin 1 Gene

Also Known as NIN1; NINJURIN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4814

About NINJ1

Cytogenetic location: 9q22.31 Genomic coordinates (GRCh38): 9:93,121,496-93,134,251 (from NCBI)

This gene has 5 transcripts (splice variants), 231 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 105.7), placenta (RPKM 42.4) and 24 other tissues.

Summary

The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009]

NINJ1 Products (1)

mRNA Protein Name
NM_004148.4 NP_004139.2 ninjurin-1

NINJ1 Protein Structure

Ninjurin

Ninjurin: Ninjurin (37 - 140)

  • 0
  • 100
  • 152 a.a.
Protein Preferred Names Protein Names

ninjurin-1

  • nerve injury-induced protein-1

NINJ1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NINJ1 Q92982 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra
NINJ1 Q92982 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
NINJ1 Q92982 CYB5R3 Homo sapiens P00387
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 CYB5R3 Homo sapiens P00387
Y2H Array
32296183
Intra
NINJ1 Q92982 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra
NINJ1 Q92982 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra
NINJ1 Q92982 CD200R1 Homo sapiens Q8TD46-4
Y2H Array
32296183
Intra
NINJ1 Q92982 CD200R1 Homo sapiens Q8TD46-4
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 CEACAM3 Homo sapiens P40198
Y2H Array
32296183
Intra
NINJ1 Q92982 CEACAM3 Homo sapiens P40198
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 TLCD4 Homo sapiens Q96MV1
Validated Y2H
32296183
Intra
NINJ1 Q92982 TLCD4 Homo sapiens Q96MV1
Y2H Array
32296183
Intra
NINJ1 Q92982 TLCD4 Homo sapiens Q96MV1
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
NINJ1 Q92982 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra
NINJ1 Q92982 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 LIME1 Homo sapiens Q9H400
Validated Y2H
32296183
Intra
NINJ1 Q92982 LIME1 Homo sapiens Q9H400
Y2H Array
32296183
Intra
NINJ1 Q92982 LIME1 Homo sapiens Q9H400
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 FCGR1A Homo sapiens P12314
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 FCGR1A Homo sapiens P12314
Y2H Array
32296183
Intra
NINJ1 Q92982 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra
NINJ1 Q92982 PVR Homo sapiens P15151
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 SGCB Homo sapiens Q16585
Y2H Array
32296183
Intra
NINJ1 Q92982 SGCB Homo sapiens Q16585
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 TIMMDC1 Homo sapiens Q9NPL8
Validated Y2H
32296183
Intra
NINJ1 Q92982 TIMMDC1 Homo sapiens Q9NPL8
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 TIMMDC1 Homo sapiens Q9NPL8
Y2H Array
32296183
Intra
NINJ1 Q92982 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra
NINJ1 Q92982 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
Intra
NINJ1 Q92982 GOLM1 Homo sapiens Q8NBJ4
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 GOLM1 Homo sapiens Q8NBJ4
Y2H Array
32296183
Intra
NINJ1 Q92982 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra
NINJ1 Q92982 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra
NINJ1 Q92982 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spondylometaphyseal Dysplasia With Corneal Dystrophy

  • SMDCD

  • Spondylometaphyseal Dysplasia-Corneal Dystrophy Syndrome

  • Smd-Corneal Dystrophy Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-Y0966 Glycine Inhibitor 99.93% Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NINJ1 VGNC VGNC:43811
Macaca mulatta NINJ1 VGNC VGNC:75350
Rattus norvegicus NINJ1 RGD RGD:3179
Mus musculus NINJ1 MGD MGI:1196617
Bos taurus NINJ1 VGNC VGNC:32078
Felis catus NINJ1 VGNC VGNC:97527
Others NINJ1 NCBI