Vamp7 - vesicle-associated membrane protein 7 Gene

Also Known as Sybl1; VAMP-7; TI-VAMP

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 20955

Summary

Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in SNARE complex assembly and positive regulation of dendrite morphogenesis. Acts upstream of or within Golgi to plasma membrane protein transport and regulation of protein targeting to vacuolar membrane. Located in several cellular components, including cytoplasmic vesicle; lamellipodium; and pseudopodium. Is expressed in several structures, including adrenal gland; genitourinary system; liver; lung; and spleen. Orthologous to human VAMP7 (vesicle associated membrane protein 7). [provided by Alliance of Genome Resources, Apr 2022]

Vamp7 Products (3)

mRNA Protein Name
NM_001302138.2 NP_001289067.1 vesicle-associated membrane protein 7 isoform 2
NM_001359151.2 NP_001346080.1 vesicle-associated membrane protein 7 isoform 3
NM_011515.6 NP_035645.1 vesicle-associated membrane protein 7 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
20871593 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within Golgi to plasma membrane protein transport IMP
IMP: Inferred from mutant phenotype
20582536 MGI
involved in SNARE complex assembly IDA
IDA: Inferred from direct assay
21151919 MGI
involved in positive regulation of dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
22171327 MGI
acts upstream of or within regulation of protein targeting to vacuolar membrane IMP
IMP: Inferred from mutant phenotype
18227281 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in Golgi apparatus IDA
IDA: Inferred from direct assay
18321981 MGI
located in apical part of cell IDA
IDA: Inferred from direct assay
14758363 MGI
located in cell surface IDA
IDA: Inferred from direct assay
21151919 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
22589474 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
19745841 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
18321981 MGI
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
15470500 MGI
located in pseudopodium IDA
IDA: Inferred from direct assay
22589474 MGI
located in transport vesicle IDA
IDA: Inferred from direct assay
19745841 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicle-associated membrane protein 7

  • synaptobrevin like 1

  • tetanus neurotoxin-insensitive vesicle-associated membrane protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Phase
HY-P10809 VAMP Inhibitor 98.13% Phase 2

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS15598 VAMP7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Vamp7 NCBI NCBI:6845