Nme8 - NME/NM23 family member 8 Gene

Also Known as Txndc3; Sptrx-2; 1700056P15Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 73412

Summary

Predicted to enable microtubule binding activity. Acts upstream of or within cellular response to Reactive Oxygen Species and flagellated sperm motility. Located in axoneme; sperm cytoplasmic droplet; and sperm principal piece. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 6. Orthologous to human NME8 (NME/NM23 family member 8). [provided by Alliance of Genome Resources, Apr 2022]

Nme8 Products (2)

mRNA Protein Name
NM_001167909.1 NP_001161381.1 thioredoxin domain-containing protein 3 isoform 2
NM_181591.3 NP_853622.2 thioredoxin domain-containing protein 3 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within cellular response to reactive oxygen species IGI
IGI: Inferred from genetic interaction
23707457 MGI
acts upstream of or within flagellated sperm motility IGI
IGI: Inferred from genetic interaction
23707457 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in axoneme IDA
IDA: Inferred from direct assay
12909633 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12909633 MGI
located in sperm cytoplasmic droplet IDA
IDA: Inferred from direct assay
12909633 MGI
located in sperm principal piece IDA
IDA: Inferred from direct assay
12909633 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thioredoxin domain-containing protein 3

  • spermatid-specific thioredoxin-2

  • thioredoxin domain containing 3 (spermatozoa)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS09379 NME8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Nme8 NCBI NCBI:51314