Mdh2 - malate dehydrogenase 2 Gene

Also Known as Mor1

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 81829

Summary

Enables L-malate dehydrogenase activity; malate dehydrogenase (NADP+) activity; and protein self-association. Involved in NADH metabolic process; dicarboxylic acid metabolic process; and tricarboxylic acid cycle. Located in mitochondrial matrix. Used to study brain ischemia; congestive heart failure; and myocardial infarction. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 51. Orthologous to human MDH2 (malate dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Mdh2 Products (1)

mRNA Protein Name
NM_031151.3 NP_112413.2 malate dehydrogenase, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables L-malate dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
12351438 RGD
enables L-malate dehydrogenase (NADP+) activity IDA
IDA: Inferred from direct assay
16737718 RGD
enables identical protein binding IDA
IDA: Inferred from direct assay
3580173 RGD
enables malate dehydrogenase activity IDA
IDA: Inferred from direct assay
1898089 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15809022 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in NADH metabolic process IDA
IDA: Inferred from direct assay
12351438 RGD
involved in malate metabolic process IDA
IDA: Inferred from direct assay
1898089 RGD
Cellular Component GO Annotation Evidence 参考文献 由来
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
6409145 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

malate dehydrogenase, mitochondrial

  • malate dehydrogenase 2, NAD (mitochondrial)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-13671 LW6 98.86% Unkown
HY-147791 MDH1-IN-2 Inhibitor 98.70% Unkown
HY-147790 MDH1-IN-1 Inhibitor 99.97% Unkown
HY-181604 MDH2-IN-2 Inhibitor / Unkown
HY-RS08261 MDH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16896 Mdh2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23338 Mdh2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Mdh2 NCBI NCBI:4191