Antibacterial agent 130
Antibacterial agent 130 is a 1,1-diarylthiogalactoside, used for targeting the Pseudomonas aeruginosa LecA. Antibacterial agent 130 shows high affinity toward LecA (Kd=1 μM). Antibacterial agent 130 has antibiofilm activity, but lacks bactericidal activity. LecA, a lectin and virulence factor from Pseudomonas aeruginosa involved in bacterial adhesion and biofilm formation.
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- CAS No.: 1502721-60-9
- 화학식: C23H28O10S
- 분자량:496.53
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Antibacterial agent 130 (compound 8a) (0.08-5 mM; 2-24 h) dose-dependently inhibits bacterial biofilm formation with 100% of inhibition at 5 mM[1].
Antibacterial agent 130 (0.01-5 mM; 24 h) has cytotoxicity against MRC-5 cell line (human fetal lung fibroblast cells) at concentration higher than 1.25 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1502721-60-9
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분자량 496.53
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화학식 C23H28O10S
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SMILES
OC[C@H]1O[C@@H](SC2=C(OC)C=CC(C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C2)[C@H](O)[C@@H](O)[C@H]1O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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