868272-50-8
868272-50-8
Chemical Structure
p38-α MAPK-IN-9
- CAS No.: 868272-50-8
- Formula:C19H20N8O2
- Molecular Weight:392.41
InChIKey: VXWYKMMJKQFNRP-UHFFFAOYSA-N
SMILES: N#CC1=C(NC(C)C)N=C(N)N=C1NC2=CC(C(NC3=NOC=C3)=O)=CC=C2C
Biological Activity: p38-α MAPK-IN-9 (Compound 25a) is a p38-α MAPK inhibitor (Ki: 0.057 nM). p38-α MAPK-IN-9 inhibits LPS (HY-D1056) induced TNFα production in hPBMCs (IC50: 18 nM)[1].
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p38-α MAPK-IN-9 | p38-α MAPK-IN-9 (Compound 25a) is a p38-α MAPK inhibitor (Ki: 0.057 nM). p38-α MAPK-IN-9 inhibits LPS (HY-D1056) induced TNFα production in hPBMCs (IC50: 18 nM). | |||||||||||||||||||||
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References
Keywords
